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Top 7 supplements for PCOS

Updated: Feb 1

Polycystic ovarian syndrome (PCOS) is a syndrome that affects up to 5 million women in the United States. In addition to a well-balanced diet and exercise routine, supplements can help support the menstrual cycles of those diagnosed with PCOS.



In the bottom right corner there is a wooden spoon filled with supplement capsules


What is PCOS?


Polycystic ovarian syndrome (PCOS) is one of the most common causes of infertility in women in the United States, affecting up to about 5 million women in the United States.


Characteristics of PCOS include:

  • Cysts on the ovaries (however, this is not the case for many women)

  • Blood sugar dysregulation (insulin resistance)

  • Hormone imbalance and increased androgens (testosterone)

  • Irregular menstrual cycles

  • Anovulatory cycles (ovulation does not take place)

  • Infertility

  • Weight gain

  • Acne

  • Excess hair growth

It is important to support the body with balanced nutrition, a regular exercise routine, and the proper supplementation. The following supplements have been shown to improve symptoms of PCOS and fertility outcomes.



Graphic listing 7 supplements for PCOS

#1 - Inositol


Inositol is a B vitamin that has proven to be one of the best supplements for women with PCOS. It supports blood sugar regulation and ovarian health.


Current studies have shown inositol to play a role in improving insulin, ovarian function and egg quality, and fertility outcomes. Inositol has also shown to help reduce inflammation, encourage weight loss, and increase HDL cholesterol (the good cholesterol).



#2 - Omega-3 Fatty Acids


This wildly known supplement is found on many grocery store shelves because of its amazing health benefits. Omega-3 fatty acids are found in fish oil and are a healthy add-on to any diet.


Omega-3's are known to help decrease inflammation and balance cholesterol levels. In women with PCOS, increased inflammation can be a cause of insulin resistance. Therefore, by decreasing inflammation, the body will be able to properly utilize insulin.




#3 - Antioxidants


N-Acetyl-Cysteine (NAC) is a potent antioxidant and amino acid that is necessary for proper endocrine health. It has similar effects as the blood sugar lowering drug, metformin, and has shown to help decrease fasting insulin and menstrual irregularities.


Pyrroloquinoline quinone (PQQ) is an antioxidant that supports the cell's mitochondria to improve egg quality, embryo implantation, and embryonic growth.



#4 - Magnesium


A study published in 2011 showed magnesium to help fasting glucose and insulin levels. By improving insulin resistance, magnesium is a very beneficial supplement for PCOS.


Magnesium is also linked to increasing energy, improving mood and hormone balance, and helping with bowel irregularities.



#5 - Vitamin D


Vitamin D deficiency is linked to insulin resistance, weight gain, and risk of heart disease and diabetes. PCOS is linked to all of these conditions as well.


Vitamin D also helps with egg maturation and development in the ovaries. Supplementing with Vitamin D will help make healthy ovarian follicles that will help with ovulation and pregnancy.



#6 - B-Complex


B vitamins, such as B12, folate (B9), and B6, are very helpful with supporting PCOS naturally by improving insulin resistance and blood glucose regulation.


B9 and inositol are shown to improve pregnancy outcomes in women with PCOS when taken together because of their ability to decrease insulin resistance. B9 can also reduce risk of miscarriage in women with PCOS.



#7 - Zinc


Zinc, when combined with saw palmetto, can help the body eliminate extra testosterone, which causes PCOS.


Zinc, because of its ability to decrease dihydrotestosterone (DHT), a powerful androgen, in the body, it is useful with decreasing excess hair growth, moodiness, and weight gain.



What are your next steps?


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Let's work together!

As a dedicated Naturopathic Doctor, I invite you to schedule a personalized 1-on-1 appointment with me. Click here to book your appointment for personalized treatments tailored to your needs.


My goal is to empower you to make your lifestyle your medicine, so I encourage you to take the first step by scheduling an appointment with me. Together, we will create a personalized plan that includes a whole foods lifestyle, exercise routines, and, if needed, nutritional supplementation.


I look forward to working with you!


*Dr. Francesca works only with patients physically located in California.*



*Disclaimer: Although I am a doctor, I may not be your doctor. The information contained within the pages of this site are for educational purposes only and should not to be used to treat conditions. Please consult with your doctor before implementing any of the treatments, diets, supplements, etc. mentioned in this blog.*


*Dr. Francesca is an affiliate for Amazon and other companies. Some links contained within the blog posts may be affiliate links from which she receives a small commission at no extra cost to the customer.*




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